Figure 1From: COPD symptoms in the morning: impact, evaluation and managementTime when COPD symptoms are worse than usual as reported by patients. *p < 0.001 versus midday, afternoon, evening, night and difficult to say group; p = 0.006 versus no particular time of the day; †p < 0.001 versus midday. Copyright © 2009, Informa Healthcare. Reproduced with permission of Informa Healthcare [3].Back to article page