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Figure 2 | Respiratory Research

Figure 2

From: Airway hyperresponsiveness is associated with airway remodeling but not inflammation in aging Cav1-/-mice

Figure 2

Thickening of subepithelial basement membrane. Using Trichrome-stained sections, morphometric analysis of thickness of bronchial epithelium (A) and thickness of subepithelial basement membrane (B) in Cav1-/- and WT mice as they age. n = 8-17. Error bars indicate SEM. Significance between age was determined by one-way ANOVA with Tukey’s post test ##p < 0.01, and ###p < 0.001. Significance between age matched Cav1-/- and WT mice was determined by Student’s T test. *p < 0.05, **p < 0.01. (C) TEM micrograph of the airway wall of a 3-month-old Cav1-/- and WT mice. Magnification is 1,700x. Black staining represents elastic fibers.

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