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Table 3 Effect of acrolein on Th1/Th2 cytokine levels in BAL fluids 48 hrs after OVA challenge †

From: Acrolein exposure suppresses antigen-induced pulmonary inflammation

 

Alum/OVA

OVA/OVA

OVA/OVA/ACR

IL-4

33.5 ± 9.3

68.6 ± 27.0

61.6 ± 10.5

IL-13

69.9 ± 28.2

139.7 ± 49.4

100.5 ± 16.1

IL-12p40

60.5 ± 7.7

600.4 ± 66.9*

194.0 ± 28.3#

TNFα

146.3 ± 41.6

96.1 ± 20.1

191.6 ± 47.6

  1. †Cytokine levels were measured by ELISA of lung lavage fluids of animals that were sensitized and challenged according to Figure 1. All values are expressed as pg/mL (mean ± SEM; n = 5–10 mice/group) and ANOVA was used to compare groups (*, p < 0.05, vs. Alum/OVA; #, p < 0.05, vs OVA/OVA).
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Respiratory Research

ISSN: 1465-993X

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