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Table 3 Effect of acrolein on Th1/Th2 cytokine levels in BAL fluids 48 hrs after OVA challenge

From: Acrolein exposure suppresses antigen-induced pulmonary inflammation

  Alum/OVA OVA/OVA OVA/OVA/ACR
IL-4 33.5 ± 9.3 68.6 ± 27.0 61.6 ± 10.5
IL-13 69.9 ± 28.2 139.7 ± 49.4 100.5 ± 16.1
IL-12p40 60.5 ± 7.7 600.4 ± 66.9* 194.0 ± 28.3#
TNFα 146.3 ± 41.6 96.1 ± 20.1 191.6 ± 47.6
  1. Cytokine levels were measured by ELISA of lung lavage fluids of animals that were sensitized and challenged according to Figure 1. All values are expressed as pg/mL (mean ± SEM; n = 5–10 mice/group) and ANOVA was used to compare groups (*, p < 0.05, vs. Alum/OVA; #, p < 0.05, vs OVA/OVA).