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Table 2 Effects of acrolein exposure on inflammatory cytokine mRNA expression from mouse lung homogenates 6 hrs after OVA challenge

From: Acrolein exposure suppresses antigen-induced pulmonary inflammation

Gene Alum/OVA OVA/OVA Alum/OVA/ACR OVA/OVA/ACR
Il4 1.00 ± 0.20 14.0 ± 4.86* 0.94 ± 0.29# 5.76 ± 1.42
Il13 1.00 ± 0.18 8.91 ± 2.47* 1.15 ± 0.37# 6.24 ± 1.89
Il12b 1.00 ± 0.17 1.28 ± 0.20 0.74 ± 0.09# 0.51 ± 0.08#
Tnf 1.00 ± 0.15 2.46 ± 0.23* 0.87 ± 0.13# 1.00 ± 0.15#
  1. Cytokine levels were measured by RT-PCR of lung homogenates from animals that were sensitized and challenged according to Figure 1. All values are normalized to Alum/OVA controls (mean ± SEM; n = 6–9 mice/group) and ANOVA was used to compare groups (*, p < 0.05 vs. Alum/OVA; #, p < 0.05 vs OVA/OVA).