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Figure 6 | Respiratory Research

Figure 6

From: Acrolein exposure suppresses antigen-induced pulmonary inflammation

Figure 6

Acrolein exposure activates the Nrf2 pathway. Lung tissue homogenates or lysis lavage samples were collected 6 hrs after a single OVA challenge and/or acrolein exposure. ( A ) Analysis of HO-1 protein levels in lysis lavage samples by Western blot. ( B ) PCR analysis of Gclm and Gclc in lung tissues. ( C ) Evaluation of biotin hydrazide-labeled proteins and whole lung lysates for the Nrf2 repressor Keap1. Band densities were quantified using Image J software. Results are expressed as mean ± SEM (n = 3-6/group) (*, p < 0.05).

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