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Table 3 Cardiopulmonary exercise testing and quality of life

From: Anxiety and depression disorders in patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension

  

No or mild

Anxiety or depression

 

Characteristic

Total

Mental disorder

Disorder (moderate to severe)

p-value

 

158

122

36

 

  6MWD, Meter

423 ± 116

431 ± 118

396 ± 106

0.162

Cardiopulmonary exercise testing

  peak VO2/kg, mL/Min/kg

12.4 ± 3.6

12.5 ± 3.7

11.9 ± 3.2

0.414

  peak VO2, ml/min

938 ± 385

946 ± 412

911 ± 275

0.652

  EqCO2 at AT, ml/min

46.3 ± 11.1

46.8 ± 10.9

44.2 ± 11.5

0.309

  VO2 at AT, ml/min

701 ± 222

693 ± 229

736 ± 194

0.442

  Oxygen pulse, (mL/min)/min-1

7.5 ± 2.2

7.4 ± 2.3

7.6 ± 2.2

0.693

  HR rest, min-1

78 ± 14

78 ± 12

77 ± 18

0.814

  HR max, min-1

123 ± 20

124 ± 20

22 ± 22

0.652

  RR sys rest, mmHg

115 ± 16

116 ± 17

110 ± 13

0.037

  RR dia rest, mmHg

76 ± 15

77 ± 16

70 ± 9

0.019

  RRsys max, mmHg

145 ± 24

148 ± 24

136 ± 24

0.010

  RR dia max, mmHg

85 ± 14

86 ± 13

81 ± 15

0.090

  Oxygen saturation rest, %

94 ± 5

94 ± 4

95 ± 5

0.289

  Oxygen saturation max, %

88 ± 9

88 ± 9

91 ± 8

0.075

  sPAP rest, mmHg

59 ± 20

59 ± 20

61 ± 20

0.628

  sPAP max, mmHg

93 ± 26

92 ± 24

95 ± 30

0.589

  Workload max, W

65 ± 26

65 ± 26

65 ± 23

0.990

  Borg dyspnoe

15 ± 2

14 ± 3

16 ± 2

0.043

  Borg PE

15 ± 2

15 ± 2

16 ± 2

0.070

Quality of life [SF-36]

  Physical functioning

37.5 ± 25.9

42.1 ± 26.6

21.4 ± 14.6

<0.001

  Physical role performance

37.4 ± 40.9

44.3 ± 42.3

14.4 ± 25.8

<0.001

  Bodily pain

70.5 ± 29.6

74.4 ± 29.3

57.2 ± 27.1

0.002

  General health perceptions

40.3 ± 19.1

43.5 ± 19.3

30.4 ± 15.1

<0.001

  Vitality

45.5 ± 18.6

49.5 ± 17.5

31.7 ± 15.5

<0.001

  Social functioning

65.9 ± 28.8

73.9 ± 25.1

39.6 ± 24.2

<0.001

  Emotional role performance

66.4 ± 48.4

76.0 ± 45.1

34.4 ± 45.9

<0.001

  Mental health

65.9 ± 18.6

71.3 ± 15.3

47.9 ± 17.6

<0.001

Laboratory parameters

NT-proBNP; pg/ml

1461 ± 2246

1477 ± 2413

1407 ± 1539

0.873

  1. Values are mean ± Standard deviation; p-values are the same for absolute values differences; 6MWD, Cardiopulmonary Exercise Testing: two-sided Student t-test, Borg Scale: Wilcoxon Rank test 6-MWD = 6-minute walking distance, VO2/kg = max.oxygen consumption/kg, EqCO2 = Ventilatory equivalent for carbon dioxide, AT = anaerobic treshold HR = heart rate, RR = Blood pressure, sys = systolic, dia = diastolic, sPAP = systolic Pulmonary arterial pressure, W = Watt.
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Respiratory Research

ISSN: 1465-993X

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