From: Comparative efficacy of long-acting bronchodilators for COPD - a network meta-analysis
 |  | Comparator | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Intervention | Â | PLACEBO | TIO 18 | SAL 50 | FOR 12 | IND 150 | IND 300 | GPM 50 | |||||||
PLACEBO | estimate | 1.00 | 0.61 | 0.67 | 0.53 | 0.55 | 0.39 | 0.60 | |||||||
95% CrI | Â | Â | 0.51 | 0.73 | 0.54 | 0.82 | 0.38 | 0.74 | 0.44 | 0.68 | 0.31 | 0.49 | 0.47 | 0.76 | |
P(better) | Â | Â | <1% | <1% | <1% | <1% | <1% | <1% | |||||||
TIO 18 | estimate | 1.63 | 1.00 | 1.09 | 0.86 | 0.89 | 0.64 | 0.97 | |||||||
95% CrI | 1.37 | 1.96 | Â | Â | 0.88 | 1.37 | 0.59 | 1.26 | 0.70 | 1.14 | 0.50 | 0.83 | 0.75 | 1.27 | |
P(better) | >99% | Â | Â | 78% | 22% | 17% | <1% | 42% | |||||||
SAL 50 | estimate | 1.50 | 0.92 | 1.00 | 0.79 | 0.82 | 0.59 | 0.89 | |||||||
95% CrI | 1.21 | 1.84 | 0.73 | 1.14 | Â | Â | 0.54 | 1.17 | 0.63 | 1.06 | 0.44 | 0.78 | 0.66 | 1.21 | |
P(better) | >99% | 22% | Â | Â | 11% | 6% | <1% | 23% | |||||||
FOR 12 | estimate | 1.90 | 1.16 | 1.26 | 1.00 | 1.03 | 0.74 | 1.13 | |||||||
95% CrI | 1.35 | 2.66 | 0.80 | 1.68 | 0.85 | 1.87 | Â | Â | 0.70 | 1.52 | 0.53 | 1.04 | 0.74 | 1.71 | |
P(better) | >99% | 78% | 89% | Â | Â | 56% | 4% | 72% | |||||||
IND 150 | estimate | 1.83 | 1.12 | 1.22 | 0.97 | 1.00 | 0.72 | 1.09 | |||||||
95% CrI | 1.48 | 2.28 | 0.88 | 1.44 | 0.95 | 1.58 | 0.66 | 1.43 | Â | Â | 0.55 | 0.94 | 0.80 | 1.50 | |
P(better) | >99% | 83% | 94% | 44% | Â | Â | 1% | 72% | |||||||
IND 300 | estimate | 2.55 | 1.56 | 1.70 | 1.35 | 1.39 | 1.00 | 1.52 | |||||||
95% CrI | 2.04 | 3.19 | 1.21 | 2.02 | 1.28 | 2.28 | 0.97 | 1.89 | 1.07 | 1.81 | Â | Â | 1.10 | 2.10 | |
P(better) | >99% | >99% | >99% | 96% | 99% | Â | Â | 99% | |||||||
GPM 50 | estimate | 1.68 | 1.03 | 1.12 | 0.89 | 0.92 | 0.66 | 1.00 | |||||||
95% CrI | 1.32 | 2.14 | 0.79 | 1.34 | 0.82 | 1.52 | 0.58 | 1.35 | 0.67 | 1.26 | 0.48 | 0.91 | Â | Â | |
P(better) | >99% | 58% | 77% | 28% | 28% | 1% | Â | Â |