From: Atopy is a risk factor for respiratory symptoms in COPD patients: results from the EUROSCOP study
Respiratory symptom | Total population | Males | Females | |||
---|---|---|---|---|---|---|
OR (95% CI) of atopy | OR (95% CI) of atopy | OR (95% CI) of atopy | ||||
Placebo | Budesonide | Placebo | Budesonide | Placebo | Budesonide | |
Wheezing at any time | 1.15 (0.71–1.87) | 0.79 (0.45–1.43) | 1.24 (0.74–2.08) | 0.92 (0.48–1.75) | 0.64 (0.15–2.78) | 0.43 (0.10–1.85) |
Cough day/night or a.m. | 1.79 (1.03–3.08) * | 0.83 (0.42–1.62) | 1.69 (0.93–3.08)# | 0.84 (0.38–1.84) | 2.52 (0.64–9.86) | 0.60 (0.17–2.08) |
Phlegm day/night or a.m. | 1.50 (0.84–2.69) | 0.91 (0.54–1.53) | 1.55 (0.82–2.93) | 0.85 (0.46–1.59) | 1.30 (0.36–4.67) | 0.92 (0.38–2.27) |
Trouble with breathing | 1.12 (0.66–1.89) | 0.68 (0.37–1.24) | 1.09 (0.59–1.99) | 0.79 (0.42–1.51) | 1.23 (0.44–3.44) | 0.22 (0.4–1.13)# |
Woken with chest tightness | 1.33 (0.74–2.38) | 1.07 (0.57–1.99) | 1.35 (0.69–2.65) | 1.08 (0.55–2.12) | 1.08 (0.27–4.34) | 1.11 (0.23–5.39) |
Attack of dyspnea after activity | 0.98 (0.59–1.62) | 1.49 (0.88–2.51) | 0.76 (0.43–1.33) | 1.55 (0.88–2.73)$ | 2.79 (0.94–8.31)# | 0.89 (0.22–3.62) |