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Table 1 Characteristics of atopic and non-atopic COPD patients in the EUROSCOP study stratified by gender

From: Atopy is a risk factor for respiratory symptoms in COPD patients: results from the EUROSCOP study

Baseline variables Males (843 patients) Females (320 patients)
  Atopic Non-atopic p. value Atopic Non-atopic p. value
  n = 181 n = 662 n = 32 n = 288  
Age, yr 53.0 (48.0–58.0) 54.0 (48.0–59.0) 0.164 51.0 (46.0–58.7) 52.0 (47.0–58.0) 0.391
Height, cm 176 (172–181) 176 (171–180) 0.403 165.5 (160.5–169.7) 165 (160–169) 0.494
Weight, kg 80.0 (72.0–88.0) 78.0 (70.0–85.0) 0.017 64.0 (58.5–73.7) 62.0 (55.0–70.0) 0.206
BMI, kg/m 2 25.3 (23.5–27.5) 24.8 (22.6–27.1) 0.016 23.8 (21.8–25.9) 22.9 (21.0–25.4) 0.205
Underweight (<18.5) 2 (1.1%) 7 (1.1%)   0 (0.0%) 17 (5.9%)  
Normal weight (18.5–24.9) 77 (42.5%) 342 (51.7%) 0.102# 20 (62.5%) 186 (64.6%) 0.277#
Overweight/Obese (≥25) 101 (55.8%) 312 (47.1%)   12 (37.5%) 84 (29.2%)  
Packyears of smoking 40.0 (29.2–55.5) 38.7 (28.5–50.0) 0.288 32.5 (26.7–36.0) 29.9 (21.3–39.0) 0.462
FEV 1 , liter * 2.7 (2.4–3.3) 2.8 (2.3–3.2) 0.680 2.1 (1.6–2.4) 2.0 (1.7–2.4) 0.904
FEV 1 % pred. * 78.7 (69.4–87.0) 79.3 (68.1–89.1) 0.685 79.4 (63.6–89.2) 80.8 (70.5–88.5) 0.666
FEV 1 %FVC * 63.9 (56.7–68.5) 64.4 (58.1–68.7) 0.443 66.4 (61.4–70.0) 65.5 (60.9–70.4) 0.823
Reversibility % pred. 2.9 (0.8–5.2) 2.8 (0.0–5.4) 0.932 3.2 (0.3–7.6) 2.9 (0.0–5.5) 0.323
Total IgE, kU/l ** 248.5 (84.0–617.2) 37.0 (15.0–82.0) <0.0001 161.0 (25.5–1373.0) 28.0 (13.0–75.0) 0.002
  1. Data are presented as median (interquartile range) or number (%). Bold p-values lower than 0.05 indicate significant differences between atopic and non-atopic patients within males or females.
  2. *Respiratory function tests were performed after inhalation of 1 mg terbutaline.
  3. **Available in 678 patients.
  4. #P.value refers to Chi-square analysis between classes of BMI and atopy.