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Table 1 Characteristics of atopic and non-atopic COPD patients in the EUROSCOP study stratified by gender

From: Atopy is a risk factor for respiratory symptoms in COPD patients: results from the EUROSCOP study

Baseline variables

Males (843 patients)

Females (320 patients)

 

Atopic

Non-atopic

p. value

Atopic

Non-atopic

p. value

 

n = 181

n = 662

n = 32

n = 288

 

Age, yr

53.0 (48.0–58.0)

54.0 (48.0–59.0)

0.164

51.0 (46.0–58.7)

52.0 (47.0–58.0)

0.391

Height, cm

176 (172–181)

176 (171–180)

0.403

165.5 (160.5–169.7)

165 (160–169)

0.494

Weight, kg

80.0 (72.0–88.0)

78.0 (70.0–85.0)

0.017

64.0 (58.5–73.7)

62.0 (55.0–70.0)

0.206

BMI, kg/m 2

25.3 (23.5–27.5)

24.8 (22.6–27.1)

0.016

23.8 (21.8–25.9)

22.9 (21.0–25.4)

0.205

Underweight (<18.5)

2 (1.1%)

7 (1.1%)

 

0 (0.0%)

17 (5.9%)

 

Normal weight (18.5–24.9)

77 (42.5%)

342 (51.7%)

0.102#

20 (62.5%)

186 (64.6%)

0.277#

Overweight/Obese (≥25)

101 (55.8%)

312 (47.1%)

 

12 (37.5%)

84 (29.2%)

 

Packyears of smoking

40.0 (29.2–55.5)

38.7 (28.5–50.0)

0.288

32.5 (26.7–36.0)

29.9 (21.3–39.0)

0.462

FEV 1 , liter *

2.7 (2.4–3.3)

2.8 (2.3–3.2)

0.680

2.1 (1.6–2.4)

2.0 (1.7–2.4)

0.904

FEV 1 % pred. *

78.7 (69.4–87.0)

79.3 (68.1–89.1)

0.685

79.4 (63.6–89.2)

80.8 (70.5–88.5)

0.666

FEV 1 %FVC *

63.9 (56.7–68.5)

64.4 (58.1–68.7)

0.443

66.4 (61.4–70.0)

65.5 (60.9–70.4)

0.823

Reversibility % pred.

2.9 (0.8–5.2)

2.8 (0.0–5.4)

0.932

3.2 (0.3–7.6)

2.9 (0.0–5.5)

0.323

Total IgE, kU/l **

248.5 (84.0–617.2)

37.0 (15.0–82.0)

<0.0001

161.0 (25.5–1373.0)

28.0 (13.0–75.0)

0.002

  1. Data are presented as median (interquartile range) or number (%). Bold p-values lower than 0.05 indicate significant differences between atopic and non-atopic patients within males or females.
  2. *Respiratory function tests were performed after inhalation of 1 mg terbutaline.
  3. **Available in 678 patients.
  4. #P.value refers to Chi-square analysis between classes of BMI and atopy.