Figure 4
Marked strain heterogeneity of respiratory DC subsets. Dissection of respiratory DC subsets with flow cytometry indicates significantly elevated plasmacytoid DC (A) numbers in 129SV mice. Respiratory CD103+ DC numbers are significantly elevated in C3H mice when compared to C57BL/6 (BL6), 129SV and DBA mice (B). Monocytic DC (MoDC) numbers are significantly elevated in C3H mice when compared to any other strain (C). CD11bhigh DC numbers are significantly elevated in 129SV mice compared to any other strain. Results are representative for n≥ 8 independent animals per strain (mean ± SEM; *p<0.05; **p<0.01; ***p<0.001).