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Figure 3 | Respiratory Research

Figure 3

From: Gene expression profiling following NRF2 and KEAP1 siRNA knockdown in human lung fibroblasts identifies CCL11/Eotaxin-1 as a novel NRF2 regulated gene

Figure 3

Modulation of Eotaxin-1 expression following KEAP1 and NRF2 siRNA knockdown. Cells were transfected with negative control siRNA targeting firefly luciferase (FFL), 1 siRNA pool targeting KEAP1 (KEAP1), and 1 siRNA pool targeting NRF2 (NRF2) and evaluated for (A) mRNA expression and (B) secreted potein levels of Eotaxin-1. Data is expressed levels relative to the FFL transfection. n=4 for each data point. A student’s t-test was performed on each data set relative to the FFL data (*p<0.5, **p<0.01). Data are represented as mean ± standard deviation.

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