Table 5 Phagocytosis activity pre and post ozone exposure
Phagocytosis | R pre ozone | R post ozone | R ozone response* | NR pre ozone | NR post ozone | NR ozone response* | Pre exposure R vs NR | Post exposure R vs NR | Ozone response R vs NR |
|---|---|---|---|---|---|---|---|---|---|
Mac (MFI) | 443 (140) | 660 (138) | 139 (59) | 412 (167) | 555 (234) | 91 (50) | ns | ns | ns |
% Mac | 34 (4) | 35 (4) | 17 (15) | 51 (6) | 44 (8) | −14 (13) | p = 0.03 | ns | ns |
Particles/Mac | 3 (1) | 4 (1) | 138 (59) | 3 (1) | 4 (2) | 91 (50) | ns | ns | ns |
% Internalized Mac | 31 (5) | 32 (4) | 26 (19) | 64 (10) | 57 (17) | −19 (21) | p = 0.02 | ns | ns |
Internal:External Particle Ratio Mac | 0.6 (0.2) | 0.5 (0.1) | 40 (27) | 2.1 (0.6) | 2.3 (0.9) | −7 (42) | p = 0.02 | ns | ns |
PMN (MFI) | 565 (144) | 542 (105) | 61 (41) | 197 (62) | 226 (27) | 78 (62) | p = 0.03 | p = 0.01 | ns |
% PMN | 26 (4) | 40 (6) | 70 (26) | 43 (5) | 33 (2) | −18 (14) | p = 0.01 | ns | p = 0.01 |
Particles/PMN | 4 (1) | 4 (1) | 66 (44) | 1 (0.3) | 2 (0.2) | 93 (58) | p = 0.03 | p = 0.02 | ns |
% Internalized PMN | 29 (4) | 46 (5) | 95 (37) | 72 (15) | 65 (14) | −5 (13) | p = 0.03 | ns | p = 0.03 |
Internal: External Particle Ratio PMN | 0.5 (0.1) | 1 (0.2) | 196 (73) | 6 (3) | 3 (2) | −6 (45) | p = 0.03 | ns | p = 0.04 |