Figure 4From: Lipoteichoic acid induces surfactant protein-A biosynthesis in human alveolar type II epithelial cells through activating the MEK1/2-ERK1/2-NF-κB pathwayEffects of lipoteichoic acid (LTA) on translocation of the transcription factor, nuclear factor (NF)-κB, from the cytoplasm to nuclei. A549 cells were exposed to 30 μg/ml LTA for 1, 6, and 24 h. Amounts of nuclear NF-κB p65 (nNF-κB) were immunodetected (A, top panel). Proliferating cell nuclear antigen (PCNA) was detected as the internal standard (bottom panel). These protein bands were quantified and analyzed (B). Each value represents the mean ± SEM for n = 6. An asterisk (*) indicates that a value significantly differed from the control groups, p < 0.05. AU, arbitrary unit.Back to article page