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Table 1 Baseline characteristics of patients with COPD referred for rehabilitation

From: Vitamin D supplementation during rehabilitation in COPD: a secondary analysis of a randomized trial

  Placebo   Vitamin D   P-value
(n = 25) (n = 25)
Antropometric data:
 Age (years) 69±6   67±8   0.464
 Gender (male/female) 19/6   19/6   1.000
 BMI (kg/m2) 24±6   25±5   0.587
 GOLD Stages      0.492
 I (n) 0   2   
 II (n) 6   7   
 III (n) 15   12   
 IV (n) 4   4   
Serum vitamin D level:      
 25-OHD (ng/ml) 20±11   23±15   0.492
Pulmonary function:
 FEV1(l) 1.06±0.28 40±10(*) 1.22±0.50 47±18(*) 0.115
 FVC (l) 2.85±0.80 83±20(*) 2.96±0.76 89±22(*) 0.328
Muscle function:      
 QF (Nm) 106±36 83±27(*) 109±41 75±20(*) 0.242
 MIP (cmH2O) −77±26 72±20(*) −67±24 63±21(*) 0.107
 MEP (cmH2O) 158±55 83±22(*) 152±50 80±26(*) 0.685
Exercise Performance:      
 6MWD (meter) 422±109 70±19(*) 391±135 65±23(*) 0.435
 VO2max (l/min) 1.21±0.48 72±24(*) 1.15±0.43 75±38(*) 0.802
 Wmax (watt) 71±27 54±22(*) 67±29 52±25(*) 0.713
Health-Related Quality of Life:
 CRDQdyspnea (points) 16.1±4.36   17.3±4.6   0.366
 CRDQtotal (points) 82.6±16.0   83.1±17.4   0.721
  1. Data are expressed as mean±SD. Values are %Pred±SD when indicated with (*). BMI = Body Mass Index; 25-OHD = Serum vitamin D level; FEV 1 = Forced Expiratory Volume in one second; FVC = Forced Vital Capacity; QF=Quadriceps Strength; MIP = Maximal Inspiratory Pressure; MEP = Maximal Expiratory Pressure; 6MWD = Six Minutes Walking Distance; VO 2max = Maximal Oxygen Uptake; W max = Maximal Workload; CRDQ dyspnea = Chronic Respiratory Disease Questionnaire (Item Dyspnea); CRDQ total = Total score on Chronic Respiratory Disease Questionnaire.