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Table 1 Baseline characteristics of patients with COPD referred for rehabilitation

From: Vitamin D supplementation during rehabilitation in COPD: a secondary analysis of a randomized trial

 

Placebo

 

Vitamin D

 

P-value

(n = 25)

(n = 25)

Antropometric data:

 Age (years)

69±6

 

67±8

 

0.464

 Gender (male/female)

19/6

 

19/6

 

1.000

 BMI (kg/m2)

24±6

 

25±5

 

0.587

 GOLD Stages

    

0.492

 I (n)

0

 

2

  

 II (n)

6

 

7

  

 III (n)

15

 

12

  

 IV (n)

4

 

4

  

Serum vitamin D level:

     

 25-OHD (ng/ml)

20±11

 

23±15

 

0.492

Pulmonary function:

 FEV1(l)

1.06±0.28

40±10(*)

1.22±0.50

47±18(*)

0.115

 FVC (l)

2.85±0.80

83±20(*)

2.96±0.76

89±22(*)

0.328

Muscle function:

     

 QF (Nm)

106±36

83±27(*)

109±41

75±20(*)

0.242

 MIP (cmH2O)

−77±26

72±20(*)

−67±24

63±21(*)

0.107

 MEP (cmH2O)

158±55

83±22(*)

152±50

80±26(*)

0.685

Exercise Performance:

     

 6MWD (meter)

422±109

70±19(*)

391±135

65±23(*)

0.435

 VO2max (l/min)

1.21±0.48

72±24(*)

1.15±0.43

75±38(*)

0.802

 Wmax (watt)

71±27

54±22(*)

67±29

52±25(*)

0.713

Health-Related Quality of Life:

 CRDQdyspnea (points)

16.1±4.36

 

17.3±4.6

 

0.366

 CRDQtotal (points)

82.6±16.0

 

83.1±17.4

 

0.721

  1. Data are expressed as mean±SD. Values are %Pred±SD when indicated with (*). BMI = Body Mass Index; 25-OHD = Serum vitamin D level; FEV 1 = Forced Expiratory Volume in one second; FVC = Forced Vital Capacity; QF=Quadriceps Strength; MIP = Maximal Inspiratory Pressure; MEP = Maximal Expiratory Pressure; 6MWD = Six Minutes Walking Distance; VO 2max = Maximal Oxygen Uptake; W max = Maximal Workload; CRDQ dyspnea = Chronic Respiratory Disease Questionnaire (Item Dyspnea); CRDQ total = Total score on Chronic Respiratory Disease Questionnaire.