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Table 3 Association with rate of decline of lung function non-Hispanic whites

From: Functional characterization of the matrix metalloproteinase-1 cigarette smoke-responsive region and association with the lung health study

SNP position in AF023338

Rs in dbSNP

Chromosome 11 position

Slow decliners

Fast decliners

P value

WW

WM

MM

WW

WM

MM

17 T/A

rs484915

102178458

73 (26%)

136 (49%)

70 (25%)

78 (31%)

117 (47%)

53 (21%)

0.35

352 G/A

rs470307

102178123

274 (98%)

7 (2%)

0

249 (99%)

2 (1%)

0

0.18

412 T/A

NA

102178063

283 (99%)

3 (1%)

0

257 (99%)

2 (1%)

0

1.00

712 G/A

rs2408490

102177763

191 (72%)

64 (24%)

9 (3%)

162 (67%)

73 (30%)

6 (2%)

0.28

759 T/G

rs7107224

102177716

200 (71%)

72 (25%)

11 (4%)

175 (68%)

77 (30%)

7 (3%)

0.44

816 A/C

rs1155764

102177659

196 (71%)

69 (25%)

11 (4%)

171 (67%)

76 (30%)

9 (3%)

0.47

1164 C/T

rs34695796

102177311

263 (96%)

12 (4%)

0

244 (97%)

7 (3%)

1 (0%)

0.36

1227 G/A

NA

102177248

277 (99%)

3 (1%)

0

251 (99%)

3 (1%)

0

1.00

1283 G/A

NA

102177192

274 (99%)

3 (1%)

0

251 (99%)

2 (1%)

0

1.00

1284 G/A

NA

102177191

247 (91%)

23 (8%)

2 (1%)

225 (90%)

25 (10%)

1 (0%)

0.74