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Table 1 Characteristics of study subjects

From: Functional characterization of the matrix metalloproteinase-1 cigarette smoke-responsive region and association with the lung health study

 

Slow decliners (n = 290)

Fast decliners (n = 261)

P value

Age

47.4 ± 0.4

49.6 ± 0.4

0.0007

Male (%)

193 (66.6)

155 (59.4)

0.082

Pack-years

38.3 ± 1.1

43.2 ± 1.2

0.002

Baseline FEV1, % predicted*

79.8 ± 0.5

74.6 ± 0.6

<0.0001

Methacholine response†

−8.0 ± 0.9

−24.2 ± 2.1

<0.0001

  1. Data are presented as percent or mean (SE).
  2. *Lung function at the start of the study as measured percent predicted FEV1 (postbronchodilator).
  3. †Measurement of the responsiveness of the airways to methacholine expressed as percent decline in FEV1 per final cumulative dose of methacholine administered (O'Connor et al. 1995).