Figure 3

Maximal drop in FEV ₁ during the early asthmatic response after the single-step challenges. (a). All subjects (n = 27), V0 represents the screening values. The mean drop in FEV₁: V0, 15.6% ± 4.3; V1, 9.6% ± 9.9; V2, 17.5% ± 14.6; V3, 11.2% ± 10.5; V411, 2% ± 15.9. The values were not different between visits 2 and 4 (p = 0.30). (b). The 15 subjects that developed LARs. The mean drop in FEV₁: V1, 11.8% ± 10.4; V2, 28.7% ± 15.3; V3, 23.8% ± 11.2; V4, 27.4% ± 18.9. The values were not different between visits 2 and 4 (p = 0.85).