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Table 2 Effect of tidal volume on PaO 2 /FiO2 of ALI rats (mmHg)

From: Low tidal volume protects pulmonary vasomotor function from “second-hit” injury in acute lung injury rats

GROUP

0h

3h

5h

F

P

CON

370.0 ± 87.0

361.9 ± 84.9

385.2 ± 40.7

0.15

0.86

ALI

436.5 ± 127.1

289.2 ± 121.6

272.1 ± 145.9

2.82

0.09

LV

321.1 ± 127.2

282.4 ± 76.0

285.0 ± 71.7

0.31

0.74

VLV

280.4 ± 140.8

195.5 ± 60.6*

166.4 ± 109.5*

1.78

0.2

MV

280.0 ± 75.0

220.3 ± 23.3

240.3 ± 25.4*

2.44

0.12

F

2.03

3.98

4.6

  

P

0.12

0.012

0.006

  
  1. PaO2/FiO2 changes. *P < 0.05 vs. CON group. CON = Control Group, ALI = Acute lung injury Group, LV = Low tidal volume Group, VLV = Very low tidal volume Group, MV = Large tidal volume Group.
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Respiratory Research

ISSN: 1465-993X

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