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Table 1 Patients’ baseline characteristics

From: A low resting heart rate at diagnosis predicts favourable long-term outcome in pulmonary arterial and chronic thromboembolic pulmonary hypertension. A prospective observational study

 

Numbers (%) Mean ± SD

Total number of patients

206

Female/male

130/76 (63/37)

Age (years)

55 ± 17

Precapillary Pulmonary arterial hypertension:

 

-Idiopathic

55 (27)

-Associated to collagen vascular disease

32 (16)

-Other associated PAH

61 (30)

-Chronic thromboembolic PH not eligible for surgery

58 (28)

NYHA functional class I/II/III/IV

1/37/104/62 (1/18/51/30)*

BMI (kg/m2)

25 ±5

Mean resting heart rate (bpm)

82 ±14

Mean arterial pressure (mmHg) †

90 ±14

Mean pulmonary arterial pressure (mmHg) †

45 ±18

Pulmonary vascular resistance (dyn*sec*m-5) †

775 ±464

Cardiac index (l/min/m2) †

2.4 ±0.8

Right atrial pressure (mmHg) †

9 ±6

NT-pro-BNP (ng/l, < 130)

1826 ±2269

6 minute walking distance (m)

386 ±137

Mean follow up (months)

45 ±35

Percentage survivors at year 1, 3, 5, 7, 9

84/67/57/55/53

Medication after baseline:

 

-Calcium antagonist

37 (18)

-Prostacyclin analogues (by inhalation)

63 (31)

-Prostacyclin analogues (parenteral)

8 (4)

-Endothelin-1 receptor antagonist

96 (47)

-Phosphodiesterase inhibitor

34 (17)

  1. * For two patients data were not registered, † measured by right heart catheter;
  2. Data is given as number (%) or mean ± SD. NYHA: New York Heart Association, WHO: World health organization, BMI: Body mass index, NT-pro-BNP: NT-pro brain natriuretic peptide.