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Table 1 Patients’ baseline characteristics

From: A low resting heart rate at diagnosis predicts favourable long-term outcome in pulmonary arterial and chronic thromboembolic pulmonary hypertension. A prospective observational study

  Numbers (%) Mean ± SD
Total number of patients 206
Female/male 130/76 (63/37)
Age (years) 55 ± 17
Precapillary Pulmonary arterial hypertension:  
-Idiopathic 55 (27)
-Associated to collagen vascular disease 32 (16)
-Other associated PAH 61 (30)
-Chronic thromboembolic PH not eligible for surgery 58 (28)
NYHA functional class I/II/III/IV 1/37/104/62 (1/18/51/30)*
BMI (kg/m2) 25 ±5
Mean resting heart rate (bpm) 82 ±14
Mean arterial pressure (mmHg) 90 ±14
Mean pulmonary arterial pressure (mmHg) 45 ±18
Pulmonary vascular resistance (dyn*sec*m-5) 775 ±464
Cardiac index (l/min/m2) 2.4 ±0.8
Right atrial pressure (mmHg) 9 ±6
NT-pro-BNP (ng/l, < 130) 1826 ±2269
6 minute walking distance (m) 386 ±137
Mean follow up (months) 45 ±35
Percentage survivors at year 1, 3, 5, 7, 9 84/67/57/55/53
Medication after baseline:  
-Calcium antagonist 37 (18)
-Prostacyclin analogues (by inhalation) 63 (31)
-Prostacyclin analogues (parenteral) 8 (4)
-Endothelin-1 receptor antagonist 96 (47)
-Phosphodiesterase inhibitor 34 (17)
  1. * For two patients data were not registered, measured by right heart catheter;
  2. Data is given as number (%) or mean ± SD. NYHA: New York Heart Association, WHO: World health organization, BMI: Body mass index, NT-pro-BNP: NT-pro brain natriuretic peptide.