Figure 7
From: Effects of hypercapnia and NO synthase inhibition in sustained hypoxic pulmonary vasoconstriction
Effects of 1400 W on the strength of HPV during normocapnia and hypercapnia. ΔPAP values in the presence of 1400 W are identical to those depicted in Figure 3 D-F and Figure 4 D-F. A. Changes in PAP (ΔPAP) during 180 min hypoxic ventilation, followed by 10 min ventilation with normoxic normocapnic gas. ΔPAP: change of PAP referenced to the value at time set at zero. B. Changes of PAP (ΔPAP) during 190 min of normoxic ventilation. ΔPAP: change of PAP referenced to the value at time set at zero. All data are mean ± SEM. *, significant difference (P < 0.05) between hypoxic normocapnia and hypoxic hypercapnic acidosis. #, significant difference (P < 0.05) between hypoxic normocapnia and hypoxic hypercapnia without acidosis. §, significant difference (P < 0.05) between hypoxic hypercapnic acidosis and hypoxic hypercapnia without acidosis.