Figure 5
From: Effects of hypercapnia and NO synthase inhibition in sustained hypoxic pulmonary vasoconstriction
Effects of L-NNA on the strength of HPV during normocapnia and hypercapnia. ΔPAP values in the presence of L-NNA are identical to those depicted in Figure 3 A-C and Figure 4 A-C. A. Changes in ΔPAP (ΔPAP) during 180 min hypoxic ventilation, followed by 10 min ventilation with normoxic normocapnic gas. ΔPAP: change of PAP referenced to the baseline value at time set at zero. B. Changes in PAP (ΔPAP) during 190 min of normoxic ventilation. ΔPAP: change of PAP referenced to the value at time set at zero. All data are mean ± SEM. §, significant difference (P < 0.05) between hypoxic hypercapnic acidosis and hypoxic hypercapnia without acidosis.