Skip to main content

Table 1 Effect of heparin tetrasaccharide on ovalbumin (OVA) induced changes in inflammatory cell influx in BAL of mice

From: Inhibition of allergic airway responses by heparin derived oligosaccharides: identification of a tetrasaccharide sequence

 

Total

Total

%

%

%

%

%

%

 

Cells

Eosinophils

Eosinophils

Epithelial

Macrophages

Lymphocytes

Neutrophils

Monocytes

(-) Control

(n = 4)

0.46 × 106

0.8 × 103

0.2%

1.1%

94.2%

3.1%

0.2%

1.2%

 

(0.04)

(0.3)

(0.1)

(0.6)

(2.6)

(2.0)

(0.1)

(0.4)

(+) Control

(n = 5)

*1.02 × 106

*0.45 × 106

*44.3%

2.3%

*30.1%

*16.9%

*5.6%

0.8%

 

(0.15)

(0.08)

(6.0)

(1.1)

(5.4)

(2.1)

(1.2)

(0.5)

Tetrasaccharide

(n = 4)

†0.60 × 106

†*0.17 × 106

†*27.7%

3.7%

†* 42.8%

*12.4%

†*9.5%

1.1%

 

(0.01)

(0.01)

(0.9)

(1.3)

(3.5)

(1.6)

(1.7)

(0.2)

  1. Data are shown as mean (SE).
  2. (-) Control (OVA sensitized/saline challenge)
  3. (+) Control (OVA sensitized/OVA challenge)
  4. Tetrasaccharide (Treatment group/OVA challenge)
  5. * p < .05 from (-) control
  6. † p < .05 from (+) control