Non-smokers | Smokers without COPD | COPD | |
---|---|---|---|
Number of subjects (M / F) | 7 (2 / 5) | 7 (6 / 1) | 6 (6 / 0) |
Age (yrs) | 57.0 ± 2.5 | 65.1 ± 3.7 | 65.7 ± 4.1 |
Current / ex-smokers | - | 4 / 3 | 0 / 6 |
Brinkman index (pack·years) | - | 53.0 ± 6.9 | 69.2 ± 12.3 |
VC (%predicted) | 107.9 ± 3.8 | 95.6 ± 3.9 * | 94.3 ± 2.1 * |
FEV1 (L) | 2.4 ± 0.1 | 2.4 ± 0.3 | 2.1 ± 0.1 |
FEV1 / FVC (%) | 83.3 ± 1.5 | 78.9 ± 2.7 | 65.7 ± 1.8 **†† |
FEV1 (%predicted) | 111.1 ± 2.6 | 101.3 ± 4.1 * | 83.5 ± 1.6 **†† |
PaO2 (mmHg) | 83.0 ± 1.6 | 76.2 ± 2.9 | 73.6 ± 4.6 |
PaCO2 (mmHg) | 39.1 ± 1.4 | 41.0 ± 1.1 | 39.3 ± 1.3 |
Type of lung cancers (number of subjects) | adenocarcinoma (5), AAH (1), metastasis of colon cancer (1), | adenocarcinoma (4), SCC (3) | adenocarcinoma (1), SCC (2), metastasis of colon cancer (1), LCC (1), LCNEC (1) |