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Table 1 Subjects’ characteristics for CLCA1 mRNA expression in induced sputum

From: Increased human Ca2+-activated Cl-channel 1 expression and mucus overproduction in airway epithelia of smokers and chronic obstructive pulmonary disease patients

 

Non-smokers

Smokers without COPD

COPD

Number of subjects (M / F)

13 (9 / 4)

5 (5 / 0)

20 (20 / 0)

Age (yrs)

29.8 ± 2.2

33.0 ± 4.9

72.3 ± 1.1 **††

Current / ex-smokers

-

5 / 0

4 / 16

Brinkman index (pack·years)

-

10.0 ± 2.4

52.1 ± 3.6

VC (%predicted)

99.0 ± 3.7

98.1 ± 2.2

97.8 ± 4.1

FEV1 (L)

3.5 ± 0.2

4.0 ± 0.3

1.4 ± 0.1 **††

FEV1 / FVC (%)

86.6 ± 1.5

88.4 ± 3.6

47.9 ± 2.0 **††

FEV1 (%predicted)

96.1 ± 3.3

101.7 ± 6.0

63.9 ± 5.7 **††

  1. Results are means ± SEMs. Comparisons between groups were made by Student's t-tests (** p ≤ 0.01, compared with non-smokers; †† p ≤ 0.01, compared with smokers without COPD.).