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Table 1 Subjects’ characteristics for CLCA1 mRNA expression in induced sputum

From: Increased human Ca2+-activated Cl-channel 1 expression and mucus overproduction in airway epithelia of smokers and chronic obstructive pulmonary disease patients

  Non-smokers Smokers without COPD COPD
Number of subjects (M / F) 13 (9 / 4) 5 (5 / 0) 20 (20 / 0)
Age (yrs) 29.8 ± 2.2 33.0 ± 4.9 72.3 ± 1.1 **††
Current / ex-smokers - 5 / 0 4 / 16
Brinkman index (pack·years) - 10.0 ± 2.4 52.1 ± 3.6
VC (%predicted) 99.0 ± 3.7 98.1 ± 2.2 97.8 ± 4.1
FEV1 (L) 3.5 ± 0.2 4.0 ± 0.3 1.4 ± 0.1 **††
FEV1 / FVC (%) 86.6 ± 1.5 88.4 ± 3.6 47.9 ± 2.0 **††
FEV1 (%predicted) 96.1 ± 3.3 101.7 ± 6.0 63.9 ± 5.7 **††
  1. Results are means ± SEMs. Comparisons between groups were made by Student's t-tests (** p ≤ 0.01, compared with non-smokers; †† p ≤ 0.01, compared with smokers without COPD.).