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Figure 2 | Respiratory Research

Figure 2

From: Increased human Ca2+-activated Cl-channel 1 expression and mucus overproduction in airway epithelia of smokers and chronic obstructive pulmonary disease patients

Figure 2

CLCA1 protein expression in airway epithelium. Immunohistochemical staining for CLCA1 in lung sections from (A) a non-smoker, (B) a smoker without COPD, and (C) a COPD patient. (A-C) Scale bars = 100 μm. CLCA1 protein was strongly expressed in the airway epithelia (bronchioles and terminal bronchioles) and minimally expressed in smooth muscles of the smoker and COPD patient. (D -F) Magnified images of panel A (D), panel B (E), and panel C (F). (G-I) Control experiments using rabbit IgG for the same lung sections from (G) a non-smoker, (H) a smoker without COPD, and (I) a COPD patient (D-I: scale bars = 40 μm).

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