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Table 3 Changes in the lung function parameters measured at clinic visits in comparison to baseline values

From: Step-down from high dose fixed combination therapy in asthma patients: a randomized controlled trial

 

BDP/F

400/24 μg/day (N = 206)

p value

FP/S

500/100 μg/day (N = 216)

p value

FEV1, L

−0.06 (0.03)

0.089

−0.06 (0.03)

0.109

FEV1% predicted

−1.72 (0.98)

0.080

−1.91 (0.98)

0.051

PEF, L/min

−2.02 (4.57)

0.658

−4.28 (4.55)

0.347

PEF % predicted

−0.90 (0.96)

0.349

−1.25 (0.95)

0.190

Daytime symptoms score

−0.06 (0.07)

0.327

−0.03 (0.06)

0.661

Night-time symptom score

0.20 (0.11)

0.067

0.07 (0.10)

0.503

  1. The values are the adjusted mean (SE) changes from baseline to the end of the study. BDP/F, beclomethasone dipropionate/formoterol; FP/S, fluticasone propionate/salmeterol; FEV1, forced expiratory volume in 1 second; PEF, peak expiratory flow.