Figure 6From: Repeated intranasal TLR7 stimulation reduces allergen responsiveness in allergic rhinitisMean total nasal morning (upper panel) and evening (lower panel) symptoms, each reflecting the preceding twelve hours, during the allergen challenge series . Symptoms were reduced on challenge days two through five in patients receiving AZD8848 (60 μg) compared with placebo, but these changes failed to reach statistical significance. Vertical bars indicate SEM.Back to article page