Figure 2From: Repeated intranasal TLR7 stimulation reduces allergen responsiveness in allergic rhinitisMean blood lymphocyte counts in the dose finding study (A) and the repeat challenge/treatment study (B). AZD8848 produced dose-dependent and repeatable lymphocyte reductions. The reductions were reversible and global, involving CD3+, CD4+, CD8+, and CD20+ cells (data not shown).Back to article page