Wk-4 | Wk1 | Wk2 | Wk3 | Wk4 | Wk5 | Wk6 | Wk7 | Wk8 | |
---|---|---|---|---|---|---|---|---|---|
Shortness of breath | 1.5(.1) | 2.0(.1) | 1.8(.1) | 1.7(.1) | 1.7(.1) | 1.7(.1) | 1.6(.1) | 1.6(.1) | 1.6(.1) |
* | * | * | * | * | ns | p=.047 | ns | ||
Cough | 1.1(.1) | 1.7(.1) | 1.3(.1) | 1.2(.1) | 1.1(.1) | 1.0(.1) | 1.0(.1) | 1.1(.1) | 1.1(.1) |
* | * | * | ns | ns | ns | ns | ns | ||
Sputum | 1.1(.1) | 1.7(.1) | 1.4(.1) | 1.2(.1) | 1.2(.1) | 1.2(.1) | 1.1(.1) | 1.1(.1) | 1.1(.1) |
* | * | * | ns | ns | ns | ns | ns | ||
Nocturnal wakening | 0.3(.1) | 0.9(.1) | 0.5(.1) | 0.5(.1) | 0.4(.1) | 0.5(.1) | 0.4(.1) | 0.4(.1) | 0.4(.1)* |
* | * | * | * | * | ns | p=.06 | p=.04 | ||
PEF, l/min | 279(8) | 264(7) | 275(8) | 276(8) | 277(8) | 277(8) | 278(8) | 277(8) | 273(7) |
* | ns | ns | ns | ns | ns | ns | ns | ||
Salbutamol , puffs/day | 1.5(.2) | 2.1(.2) | 1.8(.2) | 1.7(.2) | 1.7(.2) | 1.7(.2) | 1.8(.2) | 1.7(.2) | 1.7(.2) |
* | * | * | * | * | * | ns | ns |