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Table 2 The average symptoms scores, PEF values and number of puffs of salbutamol use are presented, starting from 4 weeks prior until 8 weeks after the onset of exacerbation

From: Prediction and course of symptoms and lung function around an exacerbation in chronic obstructive pulmonary disease

 

Wk-4

Wk1

Wk2

Wk3

Wk4

Wk5

Wk6

Wk7

Wk8

Shortness of breath

1.5(.1)

2.0(.1)

1.8(.1)

1.7(.1)

1.7(.1)

1.7(.1)

1.6(.1)

1.6(.1)

1.6(.1)

 

*

*

*

*

*

ns

p=.047

ns

Cough

1.1(.1)

1.7(.1)

1.3(.1)

1.2(.1)

1.1(.1)

1.0(.1)

1.0(.1)

1.1(.1)

1.1(.1)

 

*

*

*

ns

ns

ns

ns

ns

Sputum

1.1(.1)

1.7(.1)

1.4(.1)

1.2(.1)

1.2(.1)

1.2(.1)

1.1(.1)

1.1(.1)

1.1(.1)

 

*

*

*

ns

ns

ns

ns

ns

Nocturnal wakening

0.3(.1)

0.9(.1)

0.5(.1)

0.5(.1)

0.4(.1)

0.5(.1)

0.4(.1)

0.4(.1)

0.4(.1)*

 

*

*

*

*

*

ns

p=.06

p=.04

PEF, l/min

279(8)

264(7)

275(8)

276(8)

277(8)

277(8)

278(8)

277(8)

273(7)

 

*

ns

ns

ns

ns

ns

ns

ns

Salbutamol , puffs/day

1.5(.2)

2.1(.2)

1.8(.2)

1.7(.2)

1.7(.2)

1.7(.2)

1.8(.2)

1.7(.2)

1.7(.2)

 

*

*

*

*

*

*

ns

ns

  1. Data given are mean values, with standard errors between parentheses (repeated measurements Anova estimates). A particular week for a patient was considered evaluable if there were at least 4 valid diary days during that week.
  2. * p<0.05 for the comparison with Wk-4.