Figure 4
From: Nrf2 protects human alveolar epithelial cells against injury induced by influenza A virus
PR8 virus induces Nrf2 and HO-1 expression. ATI-like cells (a), ATII cells (b) and AM (c) were grown as described in the Methods section, infected at a MOI of 0.5 pfu/cell PR8 virus for 48 h. Panel I, relative expression of Nrf2 and HO-1 as detected by RT-PCR. Panel II, Nrf2 and HO-1 expression in alveolar cells (immunoblotting). Lane 1 – control; lane 2 – MOI of 0.5 pfu/cell PR8 virus. Relative expression of these proteins is also shown. Data represent results from three independent experiments (Mean ± SEM, * p < 0.05).