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Table 2 Airway measurements of HRCT scans in severe asthmatics with bacteria and without bacteria

From: Bacteria in sputum of stable severe asthma and increased airway wall thickness

 

Asthma with positive bacteria

Asthma without positive bacteria*

 

(n = 29)

(n = 27)

Total bronchi examined per group

401

349

Large airways > 2 mm

  

   Bronchi evaluated per patient

9.0 ± 3.7

9.2 ± 4.5

   WT/D (%)

21.3 ± 2.4

21.6 ± 2.7

   WA (%)

66.4 ± 5.4

67.5 ± 5.4

Small airways ≤ 2 mm

  

   Bronchi evaluated per patient

4.9 ± 3.3

3.9 ± 2.8

   WT/D (%)

28.4 ± 4.2

27.3 ± 3.7

   WA (%)

80.2 ± 6.9

78.7 ± 6.6

All airways

  

√WA at Pi of 10 mm

3.92 ± 0.09

4.00 ± 0.07

  1. Data are presented as mean ± SEM
  2. D = outer diameter; Pi = airway internal perimeter; WT = wall thickness; WA = wall area; WA% = percentage wall area
  3. *There were no significant differences between the groups for any of these parameters