| Respiratory Disease | Non-Inflammatory Disease | P-values | Healthy Controls | P-values |
---|
Number of Patients
| 177 | 20 | Â | 35 | Â |
Serum IgE, No. (%)
| Â | Â | Â | Â | Â |
Positive
| 97 (55%) | 1 (5%) | 0.0030* | 0 (0%) | 0.0001* |
Negative
| 80 (45%) | 19 (95%) | Â | 35 (100%) | Â |
Chlamydial DNA, No. (%)
| Â | Â | Â | Â | Â |
Positive
| 124 (70%) | 10 (50%) | 0.4417 | 7 (20%) | 0.0208* |
Negative
| 53 (30%) | 10 (50%) | Â | 28 (80%) | Â |
- Fifty five percent of patients with inflammatory respiratory disease had Chlamydia-specific IgE antibodies in their sera compared to 5% of the 20 patients with structural anomalies and 0% of healthy controls (p = 0.0030 and 0.0001 respectively. 70% of the patients diagnosed with respiratory disease also tested positive for chlamydial DNA, whereas only 20% of healthy controls tested positive for chlamydial DNA (p = 0.0208).