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Table 2 The Prevalence of Chlamydia-specific IgE in Patient Sera

From: The prevalence and identity of Chlamydia -specific IgE in children with asthma and other chronic respiratory symptoms

 

Respiratory Disease

Non-Inflammatory Disease

P-values

Healthy Controls

P-values

Number of Patients

177

20

 

35

 

Serum IgE, No. (%)

     

Positive

97 (55%)

1 (5%)

0.0030*

0 (0%)

0.0001*

Negative

80 (45%)

19 (95%)

 

35 (100%)

 

Chlamydial DNA, No. (%)

     

Positive

124 (70%)

10 (50%)

0.4417

7 (20%)

0.0208*

Negative

53 (30%)

10 (50%)

 

28 (80%)

 
  1. Fifty five percent of patients with inflammatory respiratory disease had Chlamydia-specific IgE antibodies in their sera compared to 5% of the 20 patients with structural anomalies and 0% of healthy controls (p = 0.0030 and 0.0001 respectively. 70% of the patients diagnosed with respiratory disease also tested positive for chlamydial DNA, whereas only 20% of healthy controls tested positive for chlamydial DNA (p = 0.0208).