Figure 4

Effect of exogenous insulin on pulmonary edema and alveolar fluid clearance in LPS-induced actue lung injury (n = 6 per group). (A) Total lung water content at 0, 2, 4, 8 hours after LPS or insulin treatment. (B) Alveolar fluid clearance at 0, 2, 4, 8 hours after LPS or insulin treatment. (C) Total lung water content at 8 hours after LPS-induced actue lung injury or saline treatment (D) Alveolar fluid clearance at 8 hours after LPS-induced actue lung injury or saline treatment. Albumin solution containing amiloride (5 × 10^-4 M) were injected into the alveolar spaces. Data are presented as mean ± S.E.M.ΔP < 0.05 vs Control group;ΦP < 0.05 vs Amiloride group;*P < 0.05 vs LPS group;# P < 0.05 vs LPS + Insulin group.