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Table 2 Determinants of nocturnal cough, usual cough, and chronic cough in 844 adults with asthma and in 2046 adults without asthma

From: Transient receptor potential genes, smoking, occupational exposures and cough in adults

 

Subjects with asthma

Subjects without asthma

 

Nocturnal cough

Usual cough

Chronic cough

Nocturnal cough

Usual cough

Chronic cough

Female sex

2.85 (2.10-3.86)

1.42 (1.05-1.93)

1.49 (1.02-2.17)

1.67 (1.35-2.07)

0.95 (0.73-1.23)

0.78 (0.53-1.16)

Exposure to VGDF*

1.39 (1.04-1.87)

1.29 (0.96-1.73)

1.69 (1.18-2.43)

1.09 (0.88-1.35)

0.98 (0.75-1.27)

1.05 (0.70-1.56)

Age, per 10 y

1.17 (0.96-1.42)

1.10 (0.90-1.34)

1.16 (0.90-1.48)

1.04 (0.91-1.21)

1.10 (0.91-1.32)

1.16 (0.88-1.54)

Ex smoker vs. never smoker

0.89 (0.62-1.26)

0.86 (0.60-1.24)

0.65 (0.40-1.05)

1.11 (0.85-1.46)

0.94 (0.64-1.37)

1.07 (0.57-2.01)

Current smoker vs. never smoker

1.15 (0.80-1.66)

2.04 (1.43-2.91)

2.12 (1.40-3.21)

1.68 (1.32-2.14)

3.37 (2.53-4.49)

4.26 (2.67-6.79)

≤ 16 pack-years vs. never smoker†

1.03 (0.64-1.64)

1.08 (0.67-1.74)

1.13 (0.63-2.02)

1.28 (0.93-1.76)

2.18 (1.49-3.19)

2.31 (1.24-4.33)

> 16 pack-years vs. never smoker†

1.44 (0.87-2.39)

4.45 (2.66-7.45)

3.71 (2.20-6.27)

2.34 (1.71-3.20)

5.18 (3.66-7.34)

6.43 (3.79-10.92)

Respiratory infection last 3 weeks

1.84 (1.18-2.87)

1.17 (0.76-1.82)

1.13 (0.68-1.90)

2.45 (1.74-3.44)

1.51 (1.00-2.29)

1.54 (0.84-2.83)

  1. Multivariate GEE model, adjusted for all variables in the table, principal components for within-Europe diversity, sample, and study; results are presented as OR (95% CI). Bold type indicates P < 0.05
  2. *VGDF: vapours, gases, dust, or fumes
  3. † in models without current smoker vs. never smoker. Coefficients for all other variables were basically similar (e.g.OR were for nocturnal cough 2.57, 1.27, 1.15, 0.89 and 1.67, 1.06, 1.01 and 1.13 for sex, VGDF, age and ex-smoker in subjects with and without asthma respectively)