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Table 1 Clinical characteristics, lung function testing, and hemodynamics

From: Differences of cardiac output measurements by open-circuit acetylene uptake in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension: a cohort study

  All
n = 104
PAH
n = 72
CETPH
n = 32
p
Characteristics     
Age (years) 58.1 ± 1.8 52.5 ± 2.3 70.4 ± 1.4 < 0.001
Female/male (n) 61/43 47/25 20/12 0.898
BMI (kg/m2) 25.9 ± 0.5 25.4 ± 0.6 27.4 ± 0.8 0.192
Lung function     
FVC (L) 2.98 ± 0.08 3.07 ± 0.10 2.73 ± 0.16 0.285
FVC (%) 89.9 ± 1.6 90.4 ± 1.8 86.9 ± 2.6 0.641
TLC (L) 5.41 ± 0.11 5.37 ± 0.14 5.47 ± 0.19 0.209
TLC (%) 98.1 ± 1.5 98.0 ± 1.8 95.8 ± 2.7 0.880
FEV1 (L/s) 2.09 ± 0.07 2.21 ± 0.08 1.80 ± 0.11 0.005
FEV1/FVC (%) 70.2 ± 1.0 72.2 ± 1.0 65.4 ± 2.1 0.002
TLco (%) 61.0 ± 2.1 59.9 ± 2.7 63.8 ± 2.9 0.943
pO2 at rest (mmHg) 61.2 ± 1.1 63.8 ± 1.4 54.6 ± 1.5 < 0.001
pCO2 at rest (mmHg) 30.6 ± 0.5 29.8 ± 0.6 32.3 ± 0.7 0.015
Hemodynamics     
mPAP (mmHg) 47.0 ± 1.4 46.0 ± 1.7 51.1 ± 2.2 0.255
Cardiac output (L/min) 3.96 ± 0.15 4.09 ± 0.14 3.94 ± 0.18 0.001
CI (L/min/m2) 2.27 ± 0.06 2.38 ± 0.07 2.02 ± 0.09 0.004
PVR (dyne •s/cm5) 791 ± 31 779 ± 37 843 ± 58 0.181
mRAP (mmHg) 7.2 ± 0.5 6.1 ± 0.5 10.0 ± 1.3 0.001
PCWP (mmHg) 8.8 ± 0.3 8.2 ± 0.4 10.6 ± 0.7 0.002
SVO2 (%) 58.3 ± 0.9 58.9 ± 0.9 56.7 ± 1.9 0.527
  1. Data are shown as means ± SEM.