Characteristics | AAT Genetic Modifiers Study (n= 378) | UK national registry for AATD (n= 458) | pvalue |
---|---|---|---|
Age, years | 52.2 ± 9.7 | 50.3 ± 10.4 | 0.01 |
Male sex (%) | 173 (46%) | 252 (55%) | < 0.0001 |
FEV1% predicted | 65.9 ± 33.5 | 53.8 ± 32.2 | 0.0001 |
FEV1/FVC | 0.551 ± 0.207 | 0.445 ± 0.194 | < 0.0001 |
Pack-years for ever smokers | 18.2 ± 14.5 | 15.9 ± 14.7 | < 0.0001 |