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Table 4 Baseline characteristics of patients with a 'correct' and 'false' GOLD-COPD diagnosis according to the reference-test

From: "GOLD or lower limit of normal definition? a comparison with expert-based diagnosis of chronic obstructive pulmonary disease in a prospective cohort-study"

GOLD-

COPD

FEV1/FVC

FEV1

[% pred]

FVC

[% pred]

TLC

[% pred]

RV

[% pred]

RV/TLC

[% pred]

DLCO

[% pred]

Age

[Years]

Pack years

[Years]

True

positive

0.56

(0.46; 0.64)

67

(54; 79)

94

(82; 110)

114

(103; 126)

147

(122; 177)

124

(112; 140)

62

(49; 76)

73

(70; 77)

28.0

(10.6; 52.5)

N = 211

211

211

211

207

207

207

181

211

211

False

positive

0.66

(0.61; 0.68)

98

(94; 107)

119

(108; 133)

113

(104; 120)

119

(107; 135)

103

(94; 109)

78

(70; 91)

72

(69; 78)

3.4

(0; 22.5)

N = 33

33

33

33

33

33

33

33

33

33

True

negative

0.78

(0.74; 0.83)

108

(100; 118)

112

(100; 123)

105

(97; 113)

106

(94; 116)

98

(92; 107)

82

(72; 92)

71

(67; 75)

1.1

(0; 23.8)

N = 125

125

125

125

124

124

124

119

125

125

False

negative

0.74

(0.72; 0.76)

79

(71; 85)

86

(75; 93)

104

(94; 118)

135

(106; 165)

124

(113; 146)

67

(54; 74)

73

(69; 78)

19.1

(0; 40.9)

N = 36

36

36

36

36

36

36

30

36

36

  1. COPD was defined by the GOLD definition and test results were categorized into 'correct' or 'false' according to the diagnosis of the expert-panel.
  2. FEV1/FVC, FEV1, FVC are given as post-bronchodilator values; TLC, RV and DLCO as pre-bronchodilator values.
  3. Abbreviations: as in table 1.
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Respiratory Research

ISSN: 1465-993X

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