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Table 1 Baseline characteristics of patients with and without COPD according to the expert panel and the GOLD definition

From: "GOLD or lower limit of normal definition? a comparison with expert-based diagnosis of chronic obstructive pulmonary disease in a prospective cohort-study"

 

All Subjects

Expert Panel

P

GOLD definition

P

 

(n = 405)

No COPD (n = 158)

COPD (n = 247)

 

No COPD (n = 161)

COPD (n = 244)

 

Age, years

72(69; 77)

71.5(67; 76)

73(70; 77)

0.004

72(67; 76)

73(70; 77)

0.010

Male sex, %

55.1

40.5

64.4

< 0.001

34.8

68.4

< 0.001

Death, %

14.9

6.3

20.5

< 0.001

10.6

17.8

0.047

Pack years smoking

16.8 (0; 38.8)

1.5 (0; 23)

27 (8.3; 51)

< 0.001

2.3 (0; 28)

25.2 (5.5; 51)

< 0.001

BMI, kg/m2

26.2

(24.1; 28.8)

27

(24.8; 30.1)

25.6

(23.4; 28.3)

< 0.001

27

(24.7; 30)

25.6

(23.3; 28.3)

< 0.001

Comorbidities and Symptoms

Hypertension, %

39.0

42.4

36.8

0.30

46.6

34.0

0.013

Diabetes, %

8.6

8.9

8.5

1.00

9.9

7.8

0.47

Stroke or TIA, %

22.0

17.1

25.1

0.07

18.0

24.6

0.14

Fatigue, %

41.3

46.8

37.8

0.08

46.6

37.9

0.09

Wheezing, %

63.5

55.1

68.8

0.006

59.0

66.4

0.14

COPD Inhalatory Medication

Beta2-mimetics, %

58.2

39.9

69.9

< 0.001

41.6

69.1

< 0.001

Anticholinergics, %

47.6

36.1

55.1

< 0.001

36.0

55.4

< 0.001

Inhaled Corticosteroids, %

63.0

56.3

67.2

0.035

58.4

66.0

0.14

  1. Data are shown as median (25th; 75th percentile) or %, as appropriate. P-value refers to χ2-test or Mann-Whitney-U test as appropriate.
  2. Abbreviations: BMI, body mass index, TIA, transient ischemic attack.