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Table 2 Adjusted* prevalence ratios (95% confidence interval) for cardiovascular risk factors among 7249 U.S. adults aged 20–79 years, by categories of respiratory impairment based on prebronchodilator data, National Health and Nutrition Examination Survey 2007-2010

From: Elevated cardiovascular risk among adults with obstructive and restrictive airway functioning in the United States: a cross-sectional study of the National Health and Nutrition Examination Survey from 2007–2010

 

Respiratory impairment

 
  

Obstructive impairment

 
 

None

Restrictive

Mild

Moderate/severe/ very severe

P†

Current smoking

1.00

1.23 (1.01, 1.51)

1.68 (1.40, 2.00)

2.26 (1.90, 2.70)

<0.001

Cotinine >10 ng/ml

1.00

1.23 (1.04, 1.46)

1.62 (1.37, 1.90)

2.00 (1.69, 2.36)

<0.001

Hypertension

1.00

0.99 (0.86, 1.15)

1.00 (0.88, 1.15)

1.03 (0.88, 1.21)

0.974

Total cholesterol ≥5.17 mmol/L

1.00

0.91 (0.78, 1.06)

0.90 (0.80, 1.02)

0.85 (0.73, 0.99)

0.068

High-density lipoprotein cholesterol <40 mg in men, <1.29 mmol/L in women

1.00

1.18 (1.04, 1.34)

0.95 (0.78, 1.16)

1.04 (0.85, 1.26)

0.188

Non-high-density lipoprotein cholesterol ≥130 mg/dl

1.00

0.92 (0.83, 1.01)

0.93 (0.84, 1.02)

0.86 (0.78, 0.95)

0.017

Low-density lipoprotein cholesterol ≥2.59 mmol/L‡

1.00

0.95 (0.84, 1.08)

1.00 (0.89, 1.13)

0.91 (0.80, 1.04)

0.514

C-reactive protein >3 mg/l

1.00

1.21 (1.05, 1.40)

1.02 (0.89, 1.18)

1.17 (1.03, 1.33)

0.014

Diagnosed diabetes

1.00

1.84 (1.40, 2.41)

0.70 (0.50, 0.99)

1.01 (0.68, 1.51)

<0.001

Diagnosed diabetes of fasting plasma glucose ≥7.0 mmol/L§

1.00

1.65 (1.19, 2.30)

0.45 (0.30, 0.68)

0.83 (0.54, 1.27)

<0.001

Body mass index ≥30 kg/m2

1.00

1.16 (1.03, 1.30)

0.60 (0.50, 0.72)

0.83 (0.68, 1.01)

<0.001

Abdominal obesity

1.00

1.07 (0.99, 1.16)

0.75 (0.69, 0.83)

0.96 (0.86, 1.07)

<0.001

Leisure-time physical activity <150 min/week

1.00

1.05 (0.97, 1.14)

0.99 (0.89, 1.10)

1.05 (0.97, 1.13)

0.479

  1. *Adjusted for age, gender, race or ethnicity, educational status, smoking status (except for cotinine concentration), cotinine concentration (except smoking status), systolic blood pressure (except hypertension), high-density lipoprotein cholesterol concentration (except non-high-density lipoprotein cholesterol concentration), non-high-density lipoprotein cholesterol concentration (except high-density lipoprotein cholesterol), C-reactive protein concentration, diagnosed diabetes, body mass index (except waist circumference), waist circumference (except body mass index), leisure-time physical activity, and history of congestive heart failure. Hypercholesterolemia was adjusted for all above factors except non-high-density lipoprotein cholesterol. Low-density lipoprotein cholesterol was adjusted for all factors except non-high-density lipoprotein cholesterol.
  2. †P-value for Satterthwaite adjusted F-test.
  3. ‡Sample size is 3207.
  4. §Sample size is 3263.