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Table 2 Patient characteristics and inflammatory mediators in sputum according to bronchial colonization by Haemophilus influenzae (n=116)

From: Specific IgA and metalloproteinase activity in bronchial secretions from stable chronic obstructive pulmonary disease patients colonized by Haemophilus influenzae

  Non-colonized Colonized by H. influenzae p value*
  n=94 n=22 -
Patient characteristics    
Age (years), mean (SD) 69 (9) 70 (8) 0.880
Current smoker, n (%) 24 (26) 6 (27) 0.932
Smoking pack-years, median (P25-P75) 58 (36-90) 103 (60-138) 0.002
FEV1 post-BD % pred, mean (SD) 52 (16) 50 (15) 0.597
Inhaled corticosteroids, n (%) 11 (12) 2 (9) 0.727
Inflammatory mediators in sputum    
Total cells/ml × 106, median (P25-P75) 12 (4-24) 7 (4-22) 0.388
Neutrophils/ml ×106, median (P25-P75) 7 (2-18) 4 (1-14) 0.526
IL-1β (pg/ml), median (P25-P75) 154 (41-485) 746 (121-1802) <0.001
IL-6 (pg/ml), median (P25-P75) 109 (50-201) 168 (53-436) 0.172
IL-8 (×103) (pg/ml), median (P25-P75) 8 (3-15) 16 (11-22) < 0.001
  1. *Analyses performed using chi-square, Fisher exact or Mann-Whitney U tests as required.