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Table 4 Studies which report the comparison of symptoms and quality of life

From: Statins as potential therapeutic drug for asthma?

Study Study type Group Sample (Trial/Control) Duration of treatment Results (statin group compared with the control group)
Braganza et al., [16] RCT Atorvastatin(40mg/day) vs placebo 71 4 weeks ACQ and AQLQ (p=0.005) ↑
Hothersall et al., [22] RCT Atorvastatin(40mg/day) vs placebo 54 8 weeks No significant difference
Cowan et al., [25] RCT Simvastatin(40mg/day) vs placebo 43 4 weeks ACQ (p=0.037) ↓
  1. ACQ= Asthma Control Questionnaire; AQLQ= Asthma Quality of Life Questionnaire.
  2. ↑ The symptoms and quality of life were improved in statin group compared with the control group, ↓ an opposite result.