Figure 9
From: Repair of tracheal epithelium by basal cells after chlorine-induced injury
Morphometric analysis of basal cell markers K5 and K14 in tracheal epithelium after chlorine injury. Tracheal sections stained for EdU in conjunction with either K5 or K14 were evaluated as described in Materials and Methods. (A) Volume of K5-expressing cells relative to basement membrane surface area. (B) Volume of K14-expressing cells relative to basement membrane surface area. a, p < 0.05 vs. unexposed; b, p < 0.05 vs. proximal; c, p < 0.05 vs. distal. (C) Proliferation in K5 cells measured as volume density of EdU-labeled nuclei in K5-expressing cells relative to the total epithelial nuclear volume. a, p < 0.05 vs. unexposed; b, p < 0.05 vs. proximal. (D) Proliferation in K14 cells measured as volume density of EdU-labeled nuclei in K14-expressing cells to the total epithelial nuclear volume. a, p < 0.05 vs. unexposed; b, p < 0.05 vs. proximal.