Table 3 Events (reactions and/or pathways) associated with up-regulated and down-regulated genes
Event ID* | Event Name†| P value | Input Genes in Event‡ | Total No. of Genes§ |
|---|---|---|---|---|
[Up-regulated Genes] | ||||
98458 | Immune System | 1.5e-04 | 24 | 478 |
86456 | Integrin alpha X beta 2 binds JAM-C | 7.2e-03 | 2 | 6 |
108524 | GPCR ligand binding | 3.0e-02 | 13 | 322 |
104591 | Eicosanoid ligand-binding receptors | 3.8e-02 | 2 | 13 |
23802 | Mouse JAK2 binds human common beta chain | 5.1e-04 | 2 | 2 |
89750 | Hemostasis | 1.5e-03 | 19 | 400 |
33150 | Endogenous sterols | 3.4e-02 | 2 | 13 |
108993 | Vitamin B2 metabolism | 2.9e-03 | 2 | 4 |
111211 | Stat5 tyrosine phosphorylation | 4.9e-03 | 2 | 5 |
115537 | IL7ra is phosphorylated on Y449 | 4.9e-03 | 2 | 5 |
81332 | Ubiquitination of phospho-p27/p21 | 1.6e-02 | 2 | 9 |
107910 | Synthesis, Secretion, and Deacylation of Ghrelin | 2.0e-02 | 2 | 10 |
[Down-regulated Genes] | ||||
92778 | Axon guidance | 3.9e-06 | 26 | 353 |
95727 | Myogenesis | 4.9e-02 | 2 | 13 |
90528 | Signaling by VEGF | 4.7e-04 | 4 | 14 |
100071 | Integrin cell surface interactions | 7.1e-03 | 9 | 123 |
82568 | PDGF binds to extracellular matrix proteins | 3.6e-02 | 4 | 45 |
118126 | I-Smad competes with R-Smad1/5/8 for type I receptor | 1.9e-02 | 2 | 8 |
91050 | SOS phosphorylation and dissociation | 7.3e-03 | 2 | 5 |
112933 | Cell-Cell communication | 1.7e-02 | 8 | 118 |
95483 | Metabolism of nitric oxide | 3.0e-02 | 2 | 10 |
84093 | Ethanol oxidation | 1.1e-03 | 3 | 8 |
79841 | FMO oxidizes nucleophiles | 2.3e-03 | 2 | 3 |
97703 | Apoptotic execution phase | 1.1e-02 | 5 | 49 |
107112 | Aquaporin-mediated transport | 8.0e-03 | 4 | 29 |
84730 | MAPK targets/ Nuclear events mediated by MAP kinases | 5.0e-02 | 3 | 30 |