Skip to main content

Table 2 The top 10 most up-regulated and down-regulated genes

From: Gene expression analysis of a murine model with pulmonary vascular remodeling compared to end-stage IPAH lungs

Fold-Change*

Gene Symbol

Description

[Up-regulated Genes]

72.4

Ear11

Eosinophil-associated, ribonuclease A family, member 11

46.1

Mmp12

Matrix metallopeptidase 12

11.5

Rgs1

Regulator of G-protein signaling 1

11.4

Ccl9

Chemokine ligand 9

10.3

Ccl8

Chemokine ligand 8

10.0

Igj

Immunoglobulin joining chain

9.0

Igf1

Insulin-like growth factor 1

8.2

Gpnmb

Glycoprotein nmb

8.2

Ccl11

Chemokine ligand 11

8.2

Ccl22

Chemokine ligand 22

[Down-regulated Genes]

4.2

Bex2

Brain expressed X-linked 2

3.1

Upk3b

Uroplakin 3B

2.9

Rrm2b

Ribonucleotide reductase M2 B

2.7

Lgals2

Lectin, galactoside-binding, soluble, 2

2.7

Acaa1b

Acetyl-Coenzyme A acyltransferase 1B

2.3

Shisa2

Shisa homolog 2

2.2

Ssr1

Signal sequence receptor, alpha

2.2

Kcnip4

Kv channel interacting protein 4

2.2

Msln

Mesothelin

2.1

Fam82b

Family with sequence similarity 82 member

2.1

Upk1b

Uroplakin 1B

2.1

Vldlr

Very low density lipoprotein receptor

  1. *Fold change values are calculated by dividing the experimental group values by the control values.