Table 1 Subject Characteristics.
From: Relationship between body composition, inflammation and lung function in overweight and obese asthma
| Â | Males | Females |
|---|---|---|
N (%) | 20 (45.5) | 24 (54.5) |
Age (years) | 40.8 ± 11.4 | 38.8 ± 14.9 |
BMI (kg/m2) | 32.2 ± 2.9 | 35.1 ± 3.6** |
Waist Circumference (cm) | 113.0 ± 10.1 | 107.8 ± 9.6 |
Total Body Fat (%) | 35.2 ± 5.0 | 50.3 ± 3.8*** |
Android Fat (%) | 46.2 (41.6, 51.5) | 55.8 (52.7, 59.9)*** |
Gynoid Fat (%) | 37.0 ± 4.6 | 55.6 ± 3.9*** |
Thoracic Fat (%) | 35.4 ± 5.1 | 45.9 ± 4.9*** |
FEV1 %predicted | 79.3 ± 19.5 | 83.3 ± 17.5 |
FVC %predicted | 96.7 (84.0, 98.8) | 96.4 (85.8, 107.9) |
FEV1/FVC | 66.5 (58.2, 78.9) | 73.7 (67.1, 78.4) |
TLC %predicted | 98.1 ± 13.6 | 97.6 ± 12.0 |
FRC %predicted | 101.5 ± 27.5 | 89.8 ± 19.0 |
ERV %predicted | 112.2 (87.3, 130.4) | 110.1 (93.3, 127.4) |
Atopy (%) | 100.0 | 78.3* |
ICS Dose (μg/day) †| 1000 (0, 1250) | 1000 (0, 1000) |
ICS Use (%) | 70.0 | 70.8 |
Ever Smokers (%) | 35.0 | 33.3 |
Pack Years of Ever Smokers | 8 (1, 15) | 3 (1, 7) |
Age at Asthma Diagnosis (Years) | 6 (2, 16) | 8 (3, 18) |
ACQ Score | 1.2 ± 0.7 | 1.4 ± 0.5 |
GINA Classification (%) | Â | Â |
   Intermittent | 25.0 | 12.5 |
   Mild Persistent | 20.0 | 29.2 |
   Moderate Persistent | 30.0 | 45.8 |
   Severe Persistent | 25.0 | 12.5 |
Systemic Inflammatory Markers | Â | Â |
   Leptin (μg/L) | 6.2 (4.4, 10.9) | 28.4 (19.7, 33.4)*** |
   C-Reactive Protein (mg/L) | 1.6 (0.9, 5.0) | 4.8 (2.8, 8.3)** |
Airway Inflammatory Markers | Â | Â |
   Total Cell Count (× 106/mL) | 2.6 (2.1, 4.1) | 2.0 (1.4, 5.6) |
   Neutrophils (%) | 31.3 ± 19.8 | 35.5 ± 24.9 |
   Neutrophils (× 104/mL) | 752 (321, 1641) | 1051 (277, 2709) |
   Eosinophils (%) | 4.3 (2.2, 10.3) | 1.3 (0.5, 3.3)* |
   Eosinophils (× 104/mL) | 184 (68, 375) | 100 (11, 133)* |