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Figure 4 | Respiratory Research

Figure 4

From: Impaired resolution of inflammatory response in the lungs of JF1/Msf mice following carbon nanoparticle instillation

Figure 4

Time course response markers in the lung homogenate following intratracheal (i.t.) instillation of carbon nanoparticles (CNP) in JF1/Msf (JF1) mice. (a-f) Shown are markers with remaining elevated levels at day 7 after an initial significant induction at day1 (except IL4) in response to 20 μg i.t. instillation of CNP. F7: Factor VII; IL1B: Interleukin-1beta; IL4: Interleukin-4; MDC/CCL22: Macrophage-Derived Chemokine; TNF: Tumor Necrosis Factor-alpha; vWF: von Willebrand Factor; (**) Significantly different with respect to (w.r.t) both sham control and 5 μg dose; (†) significantly different w.r.t 20 μg exposed at day1; (***) significantly different w.r.t 20 μg at day1, 5 μg and sham control. p ≤ 0.05; (n = 4 animals/experimental group).

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