From: The clinical significance of 5% change in vital capacity in patients with idiopathic pulmonary fibrosis: extended analysis of the pirfenidone trial
5% decline in VC at Month 3
No
Yes
Total*
P-value
Subjects
194
67
261*
Mortality (%)
4 (2.04)
6 (8.96)
10
0.0203
Acute exacerbation (%)
7 (3.61)
13
0.1031