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Table 3 Nasal Epithelial HO-1 Gene Expression in Healthy Subjects

From: Antioxidant components of naturally-occurring oils exhibit marked anti-inflammatory activity in epithelial cells of the human upper respiratory system

    

Fold Change from Baseline*

 

Subject#

Age (Yrs)

Gender

 

Sham Spray

Mixed Oil Spray

Mixed Oil

Fold Change

From Sham**

1

33

M

 

0.247

2.732

11.08

2

62

M

 

0.297

1.283

4.32

3

31

M

 

0.758

0.620

0.82

4

34

F

 

2.099

15.348

7.31

5

41

M

 

0.330

4.532

13.73

6

24

F

 

1.040

0.285

0.27

7

60

M

 

0.432

0.914

2.11

8

27

M

 

0.859

0.245

0.29

9

31

M

 

1.778

3.387

1.90

10

42

M

 

0.651

1.079

1.66

11

41

F

 

1.181

3.249

2.75

12

33

M

 

0.829

1.580

1.91

   

Median

0.793

1.432†

2.01

  1. *Data calculated as fold change after normalization to corresponding β-actin expression.
  2. **Values less than 1.0 indicate a decrease.
  3. †Significantly different from sham treatment (P = 0.027), Wilcoxon Signed Rank Test.