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Table 3 Nasal Epithelial HO-1 Gene Expression in Healthy Subjects

From: Antioxidant components of naturally-occurring oils exhibit marked anti-inflammatory activity in epithelial cells of the human upper respiratory system

     Fold Change from Baseline*  
Subject# Age (Yrs) Gender   Sham Spray Mixed Oil Spray Mixed Oil
Fold Change
From Sham**
1 33 M   0.247 2.732 11.08
2 62 M   0.297 1.283 4.32
3 31 M   0.758 0.620 0.82
4 34 F   2.099 15.348 7.31
5 41 M   0.330 4.532 13.73
6 24 F   1.040 0.285 0.27
7 60 M   0.432 0.914 2.11
8 27 M   0.859 0.245 0.29
9 31 M   1.778 3.387 1.90
10 42 M   0.651 1.079 1.66
11 41 F   1.181 3.249 2.75
12 33 M   0.829 1.580 1.91
    Median 0.793 1.432† 2.01
  1. *Data calculated as fold change after normalization to corresponding β-actin expression.
  2. **Values less than 1.0 indicate a decrease.
  3. †Significantly different from sham treatment (P = 0.027), Wilcoxon Signed Rank Test.