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Table 3 Differences in smoking variables by the extent of emphysema on chest CT in COPD subjects

From: Epidemiology, radiology, and genetics of nicotine dependence in COPD

 

Extent of emphysema (%)*

 

Variables

None/Trivial (<5%)

(n = 167)

Mild (5-25%)

(n = 134)

Moderate (25-50%)

(n = 31)

P

FTND severity

   

0.0008

   No/low dependence

89(44.3)

85(42.3)

27(13.4)

 

   High dependence

78(59.5)

49(37.4)

4(3.0)

 

FTND score

5.0 ± 2.4

4.7 ± 2.4

3.4 ± 2.0

0.001

Smoking starting age, years

16.6 ± 5.1

16.3 ± 4.6

15.6 ± 4.4

0.53

Pack-years of smoking

47.5 ± 22.2

57.6 ± 35.1

49.7 ± 27.7

0.01

Average number of cigarettes smoked per day

23.3 ± 9.2

25.0 ± 12.8

22.0 ± 9.4

0.24

Cigarettes/day, current

18.8 ± 10.2

16.9 ± 11.8

11.1 ± 7.3

0.001

  1. *data of extent of % emphysema were missing in 3 subjects of COPD subjects.
  2. p value for Fisher's Exact Test