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Figure 5 | Respiratory Research

Figure 5

From: Therapeutic efficacy of TBC3711 in monocrotaline-induced pulmonary hypertension

Figure 5

Effect of TBC3711 on monocrotaline (MCT)-induced pulmonary vascular remodelling. The rat lung sections were stained with elastica staining for medial wall thickness determination of pulmonary vessels in all experimental groups (a). The rat lung sections were also immunostained for α-smooth muscle actin and von Willebrand factor. (b) Proportion of non (N), partially (P) or fully (F) muscularized pulmonary vessels, as a percentage of total pulmonary vessel cross section (sized 20-50 μm) is given for different experimental groups. Bars represent mean ± SEM. One-way ANOVA with Newman-Keuls multiple comparison post-hoc test was performed for statistical analysis. ***P < 0.001.

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